Company
Lifenity International Pvt Ltd is a leader in the field of diagnostic and healthcare solutions, catered to about 24 million people for more than 3 years across India. With across 185 healthcare centers across India, Dubai and around the globe, and having more than 5 labs that are NABL accredited, our expertise lies in mass screening of predictive and inherited genetic testing.
Having created a benchmark in the diagnostic industry, Lifenity has now introduced LifeGeno as a high volume, speciality genomics laboratory in Mumbai to cater to the needs of the population.
Credentials & Accreditation:
LifeGeno is a NABL accredited laboratory in compliance with ISO 15189 standards. Adherence to these standards assures highest level of quality in medical laboratory testing.
The lab follows College of American pathologists (CAP) guidelines. The CAP is an internationally recognized organization known for its advancement of quality in laboratory medicine. Adopting to these guidelines helps laboratory professionals to provide more effective testing with consistent, high-quality results, expert interpretations thus patient's diagnoses are also accurate.
Overview
The department boasts of the latest specialized hi-end equipment. Headed by a Medical Geneticist, with more than three decades of clinical exposure in top Institutes worldwide. The technical team consists of post graduates & doctorates with extensive experience in the field of Molecular Biology & Bio-Technology. The lab is designed as per recommendations of CDC (Center for Disease Control & Prevention, USA) offering high precision diagnosis adhering to guidelines laid down by CAP (College of American Pathologists) and NABL (India). It has been approved by the Govt. of Maharashtra, Public Health Department & is registered under the Pre-Conception & Pre-natal Diagnostic Techniques Act.
Molecular biology based diagnostic tests (DNA tests by PCR, NGS, SANGER) have a greater Sensitivity & Specificity than most of the other diagnostic modalities. The instruments and kits used are all approved by CE-IVD, US-FDA, and CDSCO for diagnostic applications.
We are constantly establishing new tests for diagnosing & predicting several uncommon disease conditions. Our team’s expertise lies in R&D and establishing IVD assays. Call us up for details on new & exclusive tests available.
Besides offering highly sensitive DIAGNOSTIC TESTING, the department also offers CARRIER TESTING (for family members), PRENATAL TESTING (to know if the new-born will be normal), SUSCEPTIBILITY TESTING (to know if one is at risk), PREDICTIVE TESTING (to inform chances of developing the condition later in life), and PERSONALIZED TESTING (to know a person’s individual response to certain life saving drugs).
CYTOGENETICS:
The lab performs Tissue Culture from all human & fetal tissues, harvesting metaphases with High Resolution Giemsa Banding & other Specialized Banding like R-banding & Q-banding as indicated for specific conditions and examined for any numerical or structural abnormalities (eg: trisomy’s, translocations, deletions, etc.) on chromosomes. Using automated Karyotyping software, the patient’s chromosome charts are printed & given along with the report maintaining complete privacy and confidentiality. As per PC&PNDT act, the sex of the fetus is not revealed and is a punishable offense to do so.
FLUORESCENT IN-SITU HYBRIDIZATION (FISH):
This is a unique technology combining Cytogenetic techniques and Molecular principles. Specific probes are hybridized with the patient’s sample as per condition indicated. These are visualized under a Fluorescent Microscope. Different colored signals tell us whether the suspected condition is confirmed or excluded. FISH can be performed on direct preparations as well as on cultured cells.
MOLECULAR GENETICS & IVD ASSAY DEVELOPMENT:
In the molecular section, Nucleic Acid (DNA/RNA) based testing is done using latest, well-established techniques including Real–Time PCR, Qualitative PCR, Quantitative, PolyAcrylamide Gel Electrophoresis (PAGE), Agarose Gel Electrophoresis (AGE), Single Strand Conformation Polymorphism (SSCP), Restriction Fragment Length Polymorphism (RFLP), Reverse Transcription (RT) PCR, Oligonucleotide Hybridization and Amplification Refractory Mutation System (ARMS-PCR). The equipments and kits used are all US-FDA / CE-IVD approved for Diagnostic applications. Genetic Medicine is an ever growing field. Our Research scientists are constantly establishing new tests for diagnosis & predicting several uncommon disease conditions. Call us up for details on new tests as per your specific needs.
ADVANCED DIAGNOSTICS:
Among the Advanced technologies, we are offering Next Generation Sequencing for examining several genes together in a timely, and cost effective manner. Chromosomal Microarray offers a highly sensitive method for Molecular Karyotyping in tissues such as Abortus Material, where Conventional Cytogenetics has a high failure rate
GENETIC COUNSELING:
As Genetic diseases run in families, one affected person may mean others are carriers / at risk. Genetic Counseling is offered:
- For all syndromes & uncommon conditions
- Family pedigree is mapped for Genetic Diseases up to 4 generations
- Option of Predictive Testing is offered to relatives / persons with high risk
- Patient & family are explained about the condition with the help of charts
- Informative Hand-outs are given in certain conditions
- Prognosis of disease for the affected person is detailed
- Recurrence Risk is calculated for future pregnancy of parents of affected child
Besides the common Genetic conditions, Genetic Counseling is also offered in Congenital Hearing Loss, Retinitis Pigmentosa, Osteogenesis Imperfecta, Muscular Dystrophies, etc.
Predictive Genetic Testing
The better you know yourself, the easier you influence your body weight, youthful look, your fitness and health. Predictive genetic testing is a complete profile of your genome. In Predictive genetic testing you will learn about your genetic susceptibility for the development diseases. It can also help you in receiving new insights into your genetically determined physical characteristics and abilities, find out the effectiveness of your metabolism and your physical predispositions such as biological ageing.
Your individual analysis report will allow you to reduce the risk of developing a disease, will help the disease to be detected early on for timely treatment allow you to optimize eating habits and exercise routine in order to reach your goal much more easily.
With the help of your Predictive genetic testing you will get to know yourself not only from the medical aspect but also your day to day traits. However, we would like you to know that Predictive genetic testing does not contain any diagnosis and we recommend that you consult your physician in the case of a great change in your lifestyle.
Genetic Predisposition Panel can identify >200 diseases.
Below are some of the prominent ones:
| # | Test Name |
|---|---|
| Genetic risk for certain diseases | |
| 1 | Abdominal aortic aneurysm |
| 2 | Alzheimer |
| 3 | Asthma |
| 4 | Atrial fibrillation |
| 5 | Chronic kidney disease |
| 6 | Coeliac disease |
| 7 | Crohn’s disease |
| 8 | Diabetes mellitus type 1 |
| 9 | Diabetes mellitus type 2 |
| 10 | Gout |
| 11 | Hypertension |
| 12 | Kidney stones |
| 13 | Multiple sclerosis |
| 14 | Myocardial infarction |
| 15 | Peripheral arterial disease |
| 16 | Psoriasis |
| 17 | Rheumatoid arthritis |
| 18 | Venous Thromboembolism |
| Genetic risk factors for developing cancer | |
| 19 | Basal cell carcinoma |
| 20 | Breast cancer |
| 21 | Chronic lymphocytic leukemia |
| 22 | Colorectal cancer |
| 23 | Endometrial cancer (for Women) |
| 24 | Lung cancer |
| 25 | Melanoma |
| 26 | Ovarian cancer (for Women) |
| 27 | Prostate cancer (for Men) |
| 28 | Thyroid cancer |
| Characteristics of Metabolism | |
| 29 | Snacking Pattern |
| 30 | Blood sugar |
| 31 | Caffeine metabolism |
| # | Test Name |
|---|---|
| 32 | HDL (good) Cholesterol |
| 33 | Iron |
| 34 | Lactose metabolism |
| 35 | LDL (bad) Cholesterol |
| 36 | Potassium |
| 37 | Response to carbohydrates |
| 38 | Response to monounsaturated fats |
| 39 | Response to polyunsaturated fats |
| 40 | Response to saturated fats |
| 41 | Sodium |
| 42 | Triglycerides |
| 43 | Vitamin B12 |
| 44 | Vitamin B6 |
| 45 | Vitamin B9 |
| 46 | Vitamin D |
| 47 | Vitamin E |
| Sport and recreation in tune with your genes | |
| 48 | Achilles tendon |
| 49 | Biological ageing |
| 50 | Bone density |
| 51 | Muscle structure |
| 52 | Oxidative stress |
| 53 | Risk for being overweight |
| 54 | Strength training |
| Genetically determined conditions | |
| 55 | Alcohol addiction |
| 56 | Migraine |
| 57 | Nicotine addiction |
| 58 | Resistance to noroviruses |
| 59 | Resistance to malaria (type Duffy) |
| 60 | Schizophrenia |
| 61 | Sickle-cell disease |
| 62 | Thalassemia |
| 63 | Obesity |